erythropoietin Erythropoietin - EPO -
EPO Substance: erythropoietin Erythropoietin - EPO - hit the headlines in 1998 when the Festina-sponsored team in cycling's
Tour de France was disqualified after being caught red-handed with large quantities of it and other banned substances.
Manufactured naturally by the kidneys, EPO stimulates the production of red blood cells in bone marrow and regulates the
concentration of red blood cells and haemoglobin in the blood. This is useful for athletes, since red blood cells shuttle
oxygen to the cells, including muscle cells, enabling them to operate aerobically. EPO is a peptide hormone and can be
produced using recombinant DNA technology. By injecting EPO, athletes aim to increase their concentration of red blood
cells and, consequently, their aerobic capacity.